tag:blogger.com,1999:blog-9633767.post2107412641706246775..comments2024-03-25T09:11:17.877-07:00Comments on The Curious Wavefunction: Killing polyavians with a unistone: designing promiscuous drugsWavefunctionhttp://www.blogger.com/profile/14993805391653267639noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-9633767.post-44932984021399283102007-07-19T15:12:00.000-07:002007-07-19T15:12:00.000-07:00Yes, the review did talk about CNS drugs too. It j...Yes, the review did talk about CNS drugs too. It just seems hard to design very specific drugs having multiple but specific targets. As you said, with a good animal model, you could unwittingly reap some benefits.Wavefunctionhttps://www.blogger.com/profile/14993805391653267639noreply@blogger.comtag:blogger.com,1999:blog-9633767.post-84580705960225417512007-07-18T23:01:00.000-07:002007-07-18T23:01:00.000-07:00I guess if you had a good animal model that you co...I guess if you had a good animal model that you could use to drive the SAR then the you might (unwhittingly) end up with a promiscuous drug if that is what is needed?<BR/>Certainly a number of early CNS drugs (eg anti-psychotics) were developed like this, it was only later that the activity at multiple receptors was uncovered.chrishttps://www.blogger.com/profile/06616449115962971854noreply@blogger.com