tag:blogger.com,1999:blog-9633767.post5708463612190963268..comments2024-03-25T09:11:17.877-07:00Comments on The Curious Wavefunction: Selective vs Multitargeted Kinase Inhibitors: Still in the Stone AgeWavefunctionhttp://www.blogger.com/profile/14993805391653267639noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-9633767.post-86792625584401860562008-11-14T05:25:00.000-08:002008-11-14T05:25:00.000-08:00Sorry to be so late in commenting, but you really ...Sorry to be so late in commenting, but you really should have a look at PNAS vol. 105 pp. 16472 - 16477 '08 in which various cell lines were treated with a panel of kinase inhibitors to note which kinases were essential (1) for survival (2) for proliferation. Commonly used cancer cell lines showed widely different patterns of the kinases which were crucial, implying that the search for targets for chemotherapy won't be easy and even worse -- a general target for anti-cancer inhibitors may not exist.<BR/><BR/>RetreadAnonymousnoreply@blogger.com