The Curious Wavefunction
Musings on science, history, philosophy and literature
Showing posts with label
amyloid
.
Show all posts
Showing posts with label
amyloid
.
Show all posts
Will quantum physics help us cure Alzheimer's disease?
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There's an interesting bit of writing out in the journal ChemMedChem by Jean-Louis Kraus, a medicinal chemist in France who has worked o...
8 comments:
In which creationists' understanding of amyloid appears...tangled
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The biophysicist David Eisenberg of UCLA recently published a paper in which his group surveyed what they called the "amylome", t...
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The barrier to amyloid formation is kinetic, not thermodynamic
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One of the questions I have pondered in the past is why the functional form of a protein should correspond to its most thermodynamically sta...
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Probing amyloid, one oligomer at a time
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One of the more important paradigm shifts in our understanding of the Alzheimer’s disease-causing amyloid protein in the last few years has ...
1 comment:
Miles to go before...
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A New York Times article describes a study conducted by the NIH that basically asked scientists to simply sift through the massive evidence...
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The beta-amyloid hyp(e)othesis; the saga continues
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As Churchill would have said, beta-amyloid is a riddle, wrapped in a mystery, inside an enigma. For years now, the "amyloid hypothesis...
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A small molecule probe discriminating between Aß amyloid oligomers and fibrils
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One of the conceptual shifts that the study of Alzheimer's disease has seen in the past few years is the realization that the long-studi...
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Targeting early AD oligomers with a simple dipeptide
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A couple of days ago, an American man in Switzerland became the first human being to have his assisted suicide filmed and broadcasted on te...
Thinking about Alzheimer's Disease as Historians
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Head slumped forward, eyes closed, she could be dozing — or knocked out by the pharmacological cocktails that dull her physical and psychic ...
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Water and Amyloid Self-Assembly
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One of the most significant, interesting and yet poorly understood effect in chemistry and biology is the hydrophobic effect. An important m...
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Aß Dimers- The Long-Sought Minimal Culprit in Alzheimer's Disease?
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Following on the heels of the headline-making Nature publication that demonstrated that NSAIDs (Non-steroidal AntiInflammatory Drugs) unique...
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AD, metals, and evolution
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There always seems to be something new emerging in Alzheimer's disease research. In the last few years, at least one widely accepted hyp...
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