The Curious Wavefunction

Veteran peptide chemist Horst Kessler (TU Munich) has a good review on the effects of N-methylation of peptides and proteins in a recent ...

This is something I wanted to put out there. A colleague of mine reported a situation in which his flexible, complex organic molecule was be...

Since we were on the subject of NMR and determining conformations, I think it would be pertinent to briefly discuss one of the more slippery...

I have been thinking a lot recently about studies in which people have determined the bound conformation of a ligand by transfer-NOESY exper...

A short holiday break and a rather protracted bout of the flu have kept me from blogging. So I will link to an article of mine that just go...

This paper explores the fallacy of determining conformational energies for polar organic molecules from molecular mechanics force fields. Us...