The Curious Wavefunction

Musings on science, history, philosophy and literature

Showing posts with label macrocycles. Show all posts
Showing posts with label macrocycles. Show all posts

Macrocycles, flexibility and biological activity: A tortuous pairing

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Here's an interesting paper from the Jacobson, Wells and Walsh labs at UCSF and Stanford that seeks to demonstrate how restricting th...
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Macrocycle drug review

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Here's a comprehensive and useful review of macrocycle drugs in J Med Chem by Giordanetto and Kihlberg at AstraZeneca; well worth read...
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