An unusual epoxidation of amides

›
One of the nice reactions I remember from graduate school is the Johnson-Corey-Chaykovsky reaction which entails epoxidizing a carbonyl gro...

An industrial tour de force laid bare

›
Statins revolutionized the prevention and treatment of heart disease and saved hundreds of thousands of lives that may have been otherwise l...

Hans Bethe; his life, work and times

›
Hans Bethe was one of the most important and extraordinary scientists of the twentieth century. The sheer depth and breadth of his work is h...

A small molecule probe discriminating between Aß amyloid oligomers and fibrils

›
One of the conceptual shifts that the study of Alzheimer's disease has seen in the past few years is the realization that the long-studi...
6 comments:

An outstanding one stop shop for drug discovery and development

›
Drug discovery and development is a complex, highly multidisciplinary endeavor in which practitioners have to have knowledge about a dispara...
2 comments:

A journey with the good Lord

›
A lively Ludwig Wittgenstein tries to gently persuade Bertrand Russell of the veracity of his ideas in "Logicomix: An Epic Search for T...
5 comments:

The return of the biochemists, but let's not forget selectivity

›
James Watson has an interesting op-ed in the NYT in which he advocates a return to biochemical methods for studying cancer. Watson thinks t...

Water wires and hydrophobics

›
Quick survey of two interesting articles P. Balaram's group at the Indian Institute of Science in Bangalore has turned a serendipitous o...

The same and not the same: more aggregates in HTS

›
High-throughput screening (HTS) is now a mainstay of drug discovery and usually the starting point for most drug discovery projects. Industr...
4 comments:

Solid strands of knowledge

›
The Strand Bookstore in New York City on 12th street, close to NYU, is a book lover's paradise. Multiple copies of used and new books g...