Distinguishing statistical significance from clinical significance

›
In the past post I was talking about the difference between statistical and clinical significance and how many reported studies have appare...

How useful is cheminformatics in drug discovery?

›
Just like bioinformatics, cheminformatics has come into its own an independent framework and tool for drug design. As a measure of the field...
1 comment:

How pretty is your (im)perfect p?

›
In my first year of grad school we were once sitting in a seminar in which someone had put up a graph with a p-value in it. My advisor asked...
5 comments:

Chips worth their salt

›
This from the WSJ caught my eye today: "PepsiCo Develops 'Designer Salt' to Chip Away at Sodium Intake" Later this month,...
4 comments:

The details do matter

›
Consider a protein-ligand binding model. How easy is it to predict the best and worst binders in terms of affinity? Now, how hard is it to q...
2 comments:

Remote control of peptide screw sense

›
As is well-known, peptides helices can be right or left handed. Many details of structure, amino acid identity and orientation can control t...

Screening probes and probing screens

›
High Throughput Screening (HTS), with all its strengths and limitations, is still the single-best way to discover novel interesting molecule...

Middle Ages March

›
As far as possible I try to avoid writing about the teaching of evolution and opposition to climate change in this country because of their ...
6 comments:

A promising book falls apart

›
The atomic bombings of Hiroshima and Nagasaki were such horrific and singular historical events that any new retelling of them deserves to b...

Marshall Nirenberg (1927-2010)

›
In the latest issue of Cell, Edward Scolnick offers a moving and insightful tribute to his former mentor, Marshall Nirenberg. Nirenberg won...
1 comment: