The Curious Wavefunction

Musings on science, history, philosophy and literature

2015 Nobel Prize predictions

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The nice thing about Nobel Prizes is that it gets easier to predict them every year, simply because most of the people you nominate don...
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3 Quarks Daily annual science writing prize

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I am honored and frankly a bit stunned to hear that my post on the " fundamental philosophical dilemma " of chemistry was awarde...
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Agonists and antagonists, and why drug discovery is hard (again)

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Here's a valuable and  comprehensive review on one of the most glaring pieces of evidence for why drug discovery is so hard - the fact ...
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Prof. Erland Stevens's edX med chem class

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Just as he did previously, Prof. Erland Stevens of Davidson College is teaching a comprehensive med chem edX class that would be useful for ...

The 111 Nobel Prize nominations of Robert Burns Woodward

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As Nobel season dawns upon us, Stu Cantrill points me to an endlessly interesting link on the Nobel website which lists nominating infor...
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Peter Thiel on biotechnology again: "Get rid of the randomness"

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Peter Thiel has some provocative thoughts on biotechnology again, this time in an interview for Technology Review. I had a post earlier ...
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Cryo-electron microscopy: A prime example of a tool-driven scientific revolution

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Last week I had the immense pleasure again of having lunch with Freeman Dyson in Princeton. One of the myriad topics on the platter of in...
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Why foxes are more important than hedgehogs in drug discovery

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A while ago I wrote about the dominance of foxes over hedgehogs in chemistry. Hedgehogs love to drill deep into one topic; foxes love to...
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On live-tweeting at conferences

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Nature News has an interesting piece on another novel aspect of the collision of 21st century social media with 20th century scientific c...
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What would be a "non-intuitive" prediction in medicinal chemistry?

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Over the last two decades when computer-aided drug design was in development, one of the most common refrains you heard from medicinal ch...
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