Einstein, Oppenheimer, relativity and black holes: The curse of fundamentalitis

›
J. Robert Oppenheimer and Albert Einstein at the Institute for Advanced Study in Princeton A hundred years ago, in November, 1915, Albe...
3 comments:

The death of new reactions in medicinal chemistry?

›
JFK to medicinal chemists: Get out of your comfort zone and try out new reactions; not because it's easy, but because it's hard ...
9 comments:

The death of medicinal chemistry?

›
E. J. Corey's rational methods of chemical synthesis revolutionized organic chemistry, but they also may have been responsible for s...
5 comments:

Beware of von Neumann's elephants using bulldozers to model quarks

›
The other day I wrote about the late physicist Leo Kadanoff who captured one of the key caveats of models with a seriously useful piece o...

Linus Pauling's last laugh? Vitamin C might be bad news for mutant colorectal cancer

›
Linus Pauling holding enough rope to make sure we can hang ourselves with it if we don't run the right statistically vali...
5 comments:

Physicist Leo Kadanoff on reductionism and models: "Don't model bulldozers with quarks."

›
I have been wanting to write about Leo Kadanoff who passed away a few weeks ago. Among other things Kadanoff made seminal contributions t...
4 comments:

(Ir)rational drug design and the history of 20th century science

›
Here is an  excellent overview of the hopes and foibles of "rational" drug design by Brooke Magnanti (Hat tip: Pete Kenny ) wh...
2 comments:

"The Hunt for Vulcan": Theory, experiment, and the origin of scientific revolutions

›
Joseph Urbain La Verrier: The force of his personality and his spectacular prediction of Neptune solidified faith in the existence of Vulc...