Mohammad Movassaghi of MIT has come up with a versatile new pyridine synthesis using the coupling of amides and pi-electron donors such as acetylenes. Better than the formaldehyde guzzling Hantszch synthesis I guess. The variety of molecules produced is impressive indeed. I love em all, not their smell though. In fact I have not come across any other solvent whose smell I hated this much. Also, smelling them is apparently not very good in terms of...um...propagation purposes. At least that's what I hear.
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